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Out of the Ordinary: The Weirdest Diseases Ever Diagnosed

Human body is a creation of the wonders of the organ system, with the ability to achieve tremendous strength and go through so many biochemical reactions. But often, where there is such formidability, there can be extremes of efficiency and the caveat that it can all become very problematic in the most peculiar ways. Doctors throughout centuries have faced a number of unusual and strange weirdest diseases, which cannot be explained by the dominant perspective. From the exotic to the off putting, these conditions are things that test the norms of health and the physical body. Below are some of the weirdest diseases to have ever hit the humane society.

1. Progeria: It was called the Disease of Rapid Aging

HGPS, or progeria, is a neurogenic disorder that exhibits features of premature aging in children with an onset before the age of two years. These are apparently healthy newborns and during the first two years of life, the children start degenerating at a very fast rate. Some of the manifestations include growth retardation, wasting, thinning of the hair, skin that has the appearance of leather and joint stiffness, and cardiovascular complications. Most children with progeria approximately survive to reach the age of thirteen years, but others may survive longer. The disease is a result of a gene mutation, LMNA gene which encodes a protein central to the formation of cell nucleus structure. One must admit that progeria is one of the weirdest diseases due to the contrast between age and the patient’s appearance.

2. Alice in Wonderland Syndrome: Impairment

Just consider reading this text in the morning and the next morning rocking with the feeling like everything in the rooms is a little smaller or larger, the clock appears to be ticking differently. This is the case of those who have Alice in Wonderland Syndrome, a neurological disorder that derives its name from the famous novel. It produces momentary effects of seeing things out of shape and at the same time being disoriented. People can be aware of seeming to have their parts of the body swelling, shrinking, growing in place or changing in their size. The actual cause of AIWS is still not clearly determined but it is associated with migraine, epilepsy and some viral infections. This syndrome is notable in the list of the weirdest diseases as the one which has the most peculiar impact on perception.

3. Stone Man Syndrome: When Flesh Turns to Bone

Fibrodysplasia Ossificans Progressiva or also known as Stone Man Syndrome is an extremely rare congenital connective tissue disorder in which natural tissues transforming into bone in the human body are muscles, tendons, and ligaments. In some of these cases, the growth of the bones is abnormally directed leading to the formation of a second skeleton along the nasal plane of the body; movement is significantly limited and the child is rendered permanently crippled. This ossification process occurs even from minor forms of injury; therefore, surgeries and other related treatments are risky. FOP is a genetic disorder resulting from a mutation of the gene ACVR1, which is involved in the formation of bones. Essentially, there is no remedy for the condition and the general care given is aimed at controlling signs of the ailment and avoiding the onset of severe indications. Stone Man Syndrome undoubtedly falls among the most bizarre diseases because the process that underlies this illness is intense and has an extremely negative effect on the human body.

4. Foreign Accent Syndrome: The Effect of Change Speech

Foreign Accent Syndrome is a phenomenon, a rather rare one, experienced by a few individuals, which is characterized by the sudden occurrence of a different style of speaking that replicates a foreigner’s way of speaking. This process is often observed in cases of the closed traumatic brain injury, stroke, or any other cerebral event. Which, contrary to what the acronym might suggest, does not translate into the subject or acquiring a new language or culture, but rather distorts the child’s native language and modulates its rhythmic and tonal qualities. The precise biochemical process through which FAS occurs is not comprehensively known, although, it is considered that FAS triggers some change in the brain regions which pertain to speech. This condition is among the weirdest diseases due to the fact that its impact on an individual particularly; speech isn’t expected.

5. Walking Corpse Syndrome: Thinking That One Is Dead

Literal insanity, or Cotard’s Syndrome, is a pathological state characterized by imaginal disturbances in which the patient is convinced he or she is a corpse, dead, or stripped of internal organs. It is known that this delusion contributes to such dangerous consequences as severe depression and social isolation. The affected persons might shower infrequently, eat scarcely and avoid doctor checkups, a notion they have embraced by agreeing that it is useless to take care of a body which they believe is already dead. Cotard’s Delusion is a condition labeled with severe depression, schizophrenia, and even brain injury. The management process mainly prescribes the use of both antidepressant and antipsychotic drugs in addition to counseling. Because of the strangeness and the severity of Cotard’s Delusion, it can be classified among the most peculiar weirdest diseases in the history of medicine.

6. Alien Hand Syndrome: Thorny of the Hand aka A Hand with or without Intention 

AHS is a rarity, which implies that a person has one hand working under the person’s control but different from the other, working automatically. People with AHS can have their hand act on a stimulus it has chosen and engage in purposeless grasping as well as attempts to touch the face. This can lead to a lot of stress and result in an alteration of the normal routine of the patient’s life. AHS is typically diagnosed after surgery that involves the brain, cerebral hemorrhage, or brain inflammation that impacts the corpus callosum. To date, there is still no known treatment regimen for AHS, however, therapies such as CBT and physical restraint can be useful in controlling the symptoms. Nonetheless, Alien Hand Syndrome undoubtedly has to be considered one of the most curious diseases, as it is almost supernatural.

Conclusion

The human body is an incredible piece of work and can achieve such things, but occasionally, our Complex can become sick and get weirdest diseases that are bizarre. Such and these strange and exotic diseases and disorders make one sit up and realize anew that there is much more to health than meets the eye and there is still so much that science cannot explain. Even if a majority of these disorders are rather rare and even if not much is known about them, new research and new medical discoveries contribute to the revelation of these indeed intriguing and often very enigmatic conditions. Starting from the fast aging to thinking that a person is dead, whether the weirdest diseases ever diagnosed exist prove the variety and the uncertainty of the world.

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